TMS Saint Protocol
For Depression

TMS Saint Protocol
For Depression

TMS Saint Protocol for Rapid Depression Relief

In the vibrant landscape of Orange County, CA, a novel approach to treating depression is taking center stage – the TMS Saint Protocol. For those searching for “TMS therapy near me” or exploring innovative depression treatments, dive into the transformative realm of TMS and the revolutionary Stanford Accelerated Intelligent Neuromodulation Technique (SAINT). The SAINT protocol isn’t covered by insurance and is 100% out of pocket. Some people have the resources to cover the expense since their time may be limited. Other patients still want to go the route that insurance covers which is 5-20 minute sessions a week. Call our office and one of our experienced mental health care professionals to answer your questions on the best treatment plan for you.  85% of our clients report significant improvement. It’s Time to Feel Better!

Demystifying the SAINT Method:

Traditionally, Transcranial Magnetic Stimulation (TMS) for depression follows the DASH protocol, but the SAINT method, developed at Stanford under Dr. Nolan Williams, challenges the norm. Administering a full course of treatment – 50 sessions – over just 5 days, SAINT condenses the timeline, delivering ten-minute sessions separated by brief breaks, utilizing intermittent theta burst stimulation for rapid, high-frequency pulses.

Precision in Neuromodulation:

While all TMS targets the dorsolateral prefrontal cortex (DLPFC), SAINT introduces a novel approach. It employs resting functional connectivity MRI (fcMRI) for precise localization, making it more resource-intensive but enhancing accuracy and effectiveness compared to traditional TMS.

The Results Speak Volumes:

Two extensive studies showcase SAINT’s efficacy. The initial study, including TMS non-responders, revealed a remarkable 90% remission rate within 3-5 days. A subsequent study, excluding prior TMS recipients, confirmed a strong response with 79% achieving remission within 5 days. Although long-term durability needs further exploration, SAINT offers a dramatic antidepressant response in a fraction of the time compared to conventional TMS.

Safety and Well-Tolerance:

SAINT has been proven to be safe and well-tolerated, with reported side effects mirroring those of traditional TMS – fatigue and mild discomfort at the stimulation site. Neuropsychological testing even indicated improved cognitive flexibility among participants.

FDA Clearance and Accessibility:

The FDA officially cleared the SAINT Neuromodulation System for depression treatment in September 2022. While functional neuronavigation is integral, similar protocols can be delivered using standard brain mapping techniques. Our team at Principium Psychiatry proudly offers this accelerated TMS protocol by request, providing a path to swift relief.


The SAINT protocol emerges as a breakthrough in neuromodulation therapy, boasting a 90% remission rate in just 5 days for a treatment-resistant population. While further comparative data is awaited, SAINT provides a practical and highly effective solution for rapid relief, particularly for those unable to commit to the conventional 6-week daily treatment course.

Embark on a journey towards better mental wellness with A Better Way, and know that you’re not alone in this transformative process. We understand the challenges that come with depression, and we’re here to guide and support you. Take the first step towards a brighter tomorrow by experiencing the profound impact of SAINT – a revolutionary approach to depression relief in just 5 days. Our team is committed to providing personalized care, ensuring you feel empowered, supported, and on the path to renewed well-being. Schedule a free consultation to discuss your questions, insurance coverage, and embark on your rapid journey to mental wellness today. 

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